{"id":23834,"date":"2024-05-15T19:06:31","date_gmt":"2024-05-16T00:06:31","guid":{"rendered":"https:\/\/www.ataxia.org\/?page_id=23834"},"modified":"2025-12-17T10:06:07","modified_gmt":"2025-12-17T16:06:07","slug":"syne1","status":"publish","type":"page","link":"https:\/\/www.ataxia.org\/syne1\/","title":{"rendered":"SYNE1 Ataxia"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"23834\" class=\"elementor elementor-23834\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63690d3 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"63690d3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-08e9e7c\" data-id=\"08e9e7c\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7662af5\" data-id=\"7662af5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-790149b elementor-widget elementor-widget-heading\" data-id=\"790149b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-xl\">SYNE1 Ataxia<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3244ca7 elementor-widget elementor-widget-spacer\" data-id=\"3244ca7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47efa21 elementor-widget elementor-widget-text-editor\" data-id=\"47efa21\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #000000;\">A collection of resources for individuals and families affected by SYNE1 Ataxia.<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a7d84cf elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a7d84cf\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-c3512cf\" data-id=\"c3512cf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c840795 elementor-widget elementor-widget-text-editor\" data-id=\"c840795\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA3webinars\"><strong>WEBINARS<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-2b59944\" data-id=\"2b59944\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b07be6a elementor-widget elementor-widget-text-editor\" data-id=\"b07be6a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA3factsheet\"><strong>INFORMATION<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-04392b3\" data-id=\"04392b3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e34db2a elementor-widget elementor-widget-text-editor\" data-id=\"e34db2a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA3scasource\"><strong>RESEARCH NEWS<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-c91512c\" data-id=\"c91512c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d292c53 elementor-widget elementor-widget-text-editor\" data-id=\"d292c53\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/interland3.donorperfect.net\/weblink\/weblink.aspx?name=E79738&amp;id=285\" target=\"_blank\" rel=\"noopener\"><strong>BECOME A MEMBER &gt;&gt;<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e5fb3d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e5fb3d8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c326d5b\" data-id=\"c326d5b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1ff4fc7 elementor-widget elementor-widget-spacer\" data-id=\"1ff4fc7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22516ff elementor-widget elementor-widget-text-editor\" data-id=\"22516ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">SYNE1 Ataxia is a recessive form of Ataxia. It is caused by a genetic mutation that is passed on from parents to their children.\u202fSYNE1 Ataxia leads to problems with balance and coordination, altered reflexes, and cognitive symptoms. There are multiple names for Ataxia caused by mutations in the SYNE1 gene. This type of Ataxia can be known as:<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><ul><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Autosomal Recessive Spinocerebellar Ataxia type 8 (SCAR8)<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Autosomal Recessive Cerebellar Ataxia type 1 (ARCA1)<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">SYNE1\u202fRelated Autosomal Recessive Ataxia (SYNE1\u202fAtaxia)<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Autosomal Recessive Ataxia, Beauce type<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li><\/ul><p><span data-contrast=\"auto\">For complete information about symptoms, diagnosis, and treatment of Ataxia, visit our\u202f <\/span><span style=\"text-decoration: underline;\"><strong><a href=\"https:\/\/www.ataxia.org\/what-is-ataxia\/\">What is Ataxia?<\/a><\/strong><\/span><span data-contrast=\"auto\">\u202f page.\u202fThis page contains NAF&#8217;s resources that are specific to SYNE1 Ataxia.\u202f<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-21c5739 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"21c5739\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e2d3b39\" data-id=\"e2d3b39\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5403d92 elementor-widget elementor-widget-spacer\" data-id=\"5403d92\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3186650 elementor-widget elementor-widget-menu-anchor\" data-id=\"3186650\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA3webinars\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ace7d59 elementor-widget elementor-widget-heading\" data-id=\"ace7d59\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Webinar<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed070ae elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"ed070ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5401bab elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5401bab\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-45458e9\" data-id=\"45458e9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c481afa elementor-widget elementor-widget-heading\" data-id=\"c481afa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">All About SYNE1 Ataxia<br><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dd3d5eb elementor-widget elementor-widget-video\" data-id=\"dd3d5eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/mNT66CTRibQ&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-51b7c49 elementor-widget elementor-widget-text-editor\" data-id=\"51b7c49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em><strong>Presented by Nicolas Dupr\u00e9, MD, MSc, FRCP(C)<\/strong><\/em><\/p><p>This webinar offers an overview of SYNE1 Ataxia, including the typical diagnostic journey for those affected, what to expect for clinical care, and an overview of current research.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0e086e4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0e086e4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0721c8b\" data-id=\"0721c8b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c03b0f9 elementor-widget elementor-widget-spacer\" data-id=\"c03b0f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a31abac elementor-widget elementor-widget-menu-anchor\" data-id=\"a31abac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA3factsheet\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-280fd89 elementor-widget elementor-widget-heading\" data-id=\"280fd89\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-25b4695 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"25b4695\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-99546f2 elementor-widget elementor-widget-text-editor\" data-id=\"99546f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW56239556 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW56239556 BCX0\">SYNE1 <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> is a rare<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> neurological disorder<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> that causes people to lose their sense of balance and coordination. <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Though the gene mutations that cause SYNE1 <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> are present from birth, symptoms usually begin around age 30. <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">However, SYNE1 <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> symptoms can <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">begin as early as childhood and as late as mid-adulthood. <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">It is estimated that SYNE1 <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> accounts for around 5% of all recessive <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> cases. Though quite rare, SYNE1<\/span> <span class=\"NormalTextRun SCXW56239556 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\"> is more common in certain place, including the Beauce region of <\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">Qu\u00e9bec<\/span><span class=\"NormalTextRun SCXW56239556 BCX0\">, Canada.\u00a0<\/span><\/span><span class=\"EOP SCXW56239556 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5977cbc elementor-align-center elementor-widget elementor-widget-button\" data-id=\"5977cbc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/05\/SYNE1-Ataxia.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Printable Fact Sheet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-46ec8d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"46ec8d8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c5176f\" data-id=\"5c5176f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-baba714 elementor-widget elementor-widget-heading\" data-id=\"baba714\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Symptoms<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e68c560 elementor-widget elementor-widget-text-editor\" data-id=\"e68c560\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">Typically, the first SYNE1 Ataxia symptoms to be noticed are balance and coordination problems. Other common symptoms include trouble with speaking and swallowing, as well as jumpy or double vision. People with SYNE1 Ataxia can also have cognitive changes, such as problems with attention, executive functioning, and working memory.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Less common symptoms include altered reflexes and scoliosis.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b5a8a8c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b5a8a8c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3457ef0\" data-id=\"3457ef0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cbea4a9 elementor-widget elementor-widget-heading\" data-id=\"cbea4a9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Prognosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a0a1c83 elementor-widget elementor-widget-text-editor\" data-id=\"a0a1c83\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW114091761 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW114091761 BCX0\">The symptoms of <\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">SYNE1 <\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW114091761 BCX0\"> typically begin<\/span><span class=\"NormalTextRun SCXW114091761 BCX0\"> around age 30, <\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">but childhood onset or later adult onset have also been reported.<\/span> <span class=\"NormalTextRun SCXW114091761 BCX0\">The condition is slowly progressive and may require a cane, walker, or rarely a wheelchair later in life. Life span is not shortened.<\/span> <span class=\"NormalTextRun SCXW114091761 BCX0\">Currently there is no cure for <\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">SYNE1 <\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW114091761 BCX0\">.<\/span><\/span><span class=\"EOP SCXW114091761 BCX0\" data-ccp-props=\"{}\"> Treatments such as physiotherapy, occupational therapy, and speech-language therapy can significantly improve the lives of people with SYNE1 Ataxia.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8fd72fe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8fd72fe\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0b15faa\" data-id=\"0b15faa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3658576 elementor-widget elementor-widget-heading\" data-id=\"3658576\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Genetics<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e0f520 elementor-widget elementor-widget-text-editor\" data-id=\"3e0f520\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">SYNE1 Ataxia is an inherited genetic disorder. It is caused by an abnormality of a single gene called the <\/span><i><span data-contrast=\"auto\">SYNE1<\/span><\/i><span data-contrast=\"auto\"> gene. The abnormality can be passed from generation to generation by family members who carry it. Males and females are equally likely to inherit the genes that cause FA.\u202f<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Inherited diseases like SYNE1 Ataxia occur when one pair of the body\u2019s 20,000 genes does not work properly. Genes are microscopic structures within the cells of our bodies that contain instructions for every feature we inherit from our parents. Two copies of each gene are inherited; one copy from the mother and one from the father. SYNE1 Ataxia is autosomal recessive, which means that an individual only develops symptoms of the disease if both copies of his\/her <em>SYNE1<\/em> gene are not working properly.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">An individual who has one copy of an altered or nonfunctioning <\/span><i><span data-contrast=\"auto\">SYNE1<\/span><\/i><span data-contrast=\"auto\"> gene does not develop any neurological symptoms and is called a carrier. For people who are carriers, the normal <\/span><i><span data-contrast=\"auto\">SYNE1<\/span><\/i><span data-contrast=\"auto\"> gene compensates for the nonfunctioning copy of the gene. However, a child whose parents are both carriers can inherit a \u201cdouble dose\u201d of the altered <\/span><i><span data-contrast=\"auto\">SYNE1<\/span><\/i><span data-contrast=\"auto\"> gene and will therefore develop SYNE1 Ataxia.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Most of the time carriers have no idea that they have an abnormal <\/span><i><span data-contrast=\"auto\">SYNE1<\/span><\/i><span data-contrast=\"auto\"> gene because they do not have symptoms or medical problems that go along with being a carrier. It is often only when a child is diagnosed with SYNE1 Ataxia that the parents learn that they are both carriers. When both parents are carriers, each of their children has a 25 percent chance of having SYNE1 Ataxia and a 50 percent chance of being a carrier.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">In rare cases, SYNE1 Ataxia can also be caused by compound heterozygous mutations. Compound heterozygous describes a situation where someone has two different mutations in the SYNE1 gene, one in one gene copy and one in the other. Even though the mutations are slightly different from each other, when combined they still cause SYNE1 Ataxia.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-74dbb25 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"74dbb25\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-804ea44\" data-id=\"804ea44\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-33799d8 elementor-widget elementor-widget-heading\" data-id=\"33799d8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Diagnosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-53802fc elementor-widget elementor-widget-text-editor\" data-id=\"53802fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW224551047 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224551047 BCX0\">A neurologic examination can <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">determine<\/span><span class=\"NormalTextRun SCXW224551047 BCX0\"> whether a person has symptoms typical of SYNE1 <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">. A neurologist is often the most helpful specialist in recognizing symptoms and diagnosing the disease that causes <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">Ataxia<\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">. A CT or MRI scan of the brain may show atrophy of the cerebellum. However, a specific diagnosis of <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">SYNE1 <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">Ataxia<\/span> <span class=\"NormalTextRun SCXW224551047 BCX0\">can only be made by a genetic test. This genetic test is sometimes clearly abnormal, but other times it is difficult to interpret. The test results often need to be evaluated by an expert in <\/span><span class=\"NormalTextRun SCXW224551047 BCX0\">medical genetics.<\/span><\/span><span class=\"EOP SCXW224551047 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-378fb98 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"378fb98\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d439f8e\" data-id=\"d439f8e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b9901f elementor-widget elementor-widget-spacer\" data-id=\"1b9901f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ea94b0 elementor-widget elementor-widget-menu-anchor\" data-id=\"4ea94b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA3scasource\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bcbef3d elementor-widget elementor-widget-heading\" data-id=\"bcbef3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SYNE1 Ataxia Research News<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b83a649 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"b83a649\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dda425b elementor-widget elementor-widget-text-editor\" data-id=\"dda425b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>SCAsource provides Ataxia research news, directly from researchers to the Ataxia community. <span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Visit\u00a0<\/span><strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.ataxia.org\/SCAsource\" target=\"_blank\" rel=\"noopener\">SCAsource<\/a><\/span><\/strong><span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"> to see their full collection.\u00a0<\/span>Here is a collection of articles relevant to SYNE1 Ataxia.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a35336 elementor-widget elementor-widget-spacer\" data-id=\"8a35336\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7906cba elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-posts--thumbnail-top elementor-widget elementor-widget-posts\" data-id=\"7906cba\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;3&quot;,&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:35,&quot;sizes&quot;:[]},&quot;classic_row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-23239 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-speech-language-pathology tag-symptoms tag-talking\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-articulation\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/Apr-12-Featured-Image-300x157.png\" class=\"attachment-medium size-medium wp-image-23240\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/Apr-12-Featured-Image-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/Apr-12-Featured-Image-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/Apr-12-Featured-Image-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/Apr-12-Featured-Image.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-articulation\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Articulation?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tApril 12, 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Articulation refers to the ability to produce speech sounds using the tongue, lips, jaw, and the roof of your mouth. All of these organs are also known as articulators. The <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-articulation\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-22620 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-speech-language-pathology tag-symptoms tag-talking\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-300x157.png\" class=\"attachment-medium size-medium wp-image-22621\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is intelligibility?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tJanuary 19, 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Speech intelligibility refers to how many words can be correctly understood by a listener. For example, if someone says the phrase, \u201cMy name is John,\u201d and a listener hears, \u201cMy <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19471 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-cerebellum-function tag-english tag-eye-function tag-nystagmus\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-nystagmus\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_1477334069-768x512-1-300x200.webp\" class=\"attachment-medium size-medium wp-image-19519\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_1477334069-768x512-1-300x200.webp 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_1477334069-768x512-1.webp 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-nystagmus\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Nystagmus?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tDecember 10, 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Nystagmus, also known as ocular ataxia, is a term that refers to uncontrollable eye movement- usually a repetitive cycle of slow movement in a specific direction followed by a quick <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-nystagmus\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19415 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-arsacs tag-ataxia tag-english tag-genetic-testing\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-300x157.png\" class=\"attachment-medium size-medium wp-image-20153\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is recessive ataxia?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tNovember 29, 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>What is a recessive disorder? A recessive disorder is one that has a specific disease mechanism. For a recessive disorder to occur, both copies of the causative gene must be <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-852 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-mri\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-magnetic-resonance-imaging-mri\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"160\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/B.L-Edlow-et-al-Brain-MRI-300x160-1.jpg\" class=\"attachment-medium size-medium wp-image-19617\" alt=\"\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-magnetic-resonance-imaging-mri\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Magnetic Resonance Imaging (MRI)?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tNovember 15, 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>What is it? Magnetic resonance imaging (MRI) is a type of technology used to take detailed pictures of the body. It is commonly used to detect abnormalities in the body, <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-magnetic-resonance-imaging-mri\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-528 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-cerebellum-function tag-english tag-unknown-ataxia-type\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-the-cerebellum\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"233\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/669px-Gehirn_lateral_-_Lobi__Stammhirn__Cerebellum_eng.svg_-300x233.png\" class=\"attachment-medium size-medium wp-image-19603\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/669px-Gehirn_lateral_-_Lobi__Stammhirn__Cerebellum_eng.svg_-300x233.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/669px-Gehirn_lateral_-_Lobi__Stammhirn__Cerebellum_eng.svg_.png 669w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-the-cerebellum\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is the Cerebellum?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tJuly 12, 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>The cerebellum, often referred to as the \u201clittle brain\u201d, is part of the brain that is located behind the cerebrum (forebrain). The cerebellum accounts for about 10% of the brain\u2019s <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-the-cerebellum\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>SYNE1 Ataxia A collection of resources for individuals and families affected by SYNE1 Ataxia. WEBINARS INFORMATION RESEARCH NEWS BECOME A MEMBER &gt;&gt; SYNE1 Ataxia is a recessive form of Ataxia. <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-the-cerebellum\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":4,"featured_media":21512,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-23834","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>SYNE1 Ataxia - National Ataxia Foundation<\/title>\n<meta name=\"description\" content=\"Learn about SYNE1 Ataxia, a rare neurodegenerative disorder. Explore symptoms, genetics, and current research initiatives.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ataxia.org\/syne1\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SYNE1 Ataxia - National Ataxia Foundation\" \/>\n<meta property=\"og:description\" content=\"Learn about SYNE1 Ataxia, a rare neurodegenerative disorder. Explore symptoms, genetics, and current research initiatives.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ataxia.org\/syne1\/\" \/>\n<meta property=\"og:site_name\" content=\"National Ataxia Foundation\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-17T16:06:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/05\/Ataxia-Type-Featured-Image.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/syne1\\\/\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/syne1\\\/\",\"name\":\"SYNE1 Ataxia - National Ataxia Foundation\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/syne1\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/syne1\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Ataxia-Type-Featured-Image.png\",\"datePublished\":\"2024-05-16T00:06:31+00:00\",\"dateModified\":\"2025-12-17T16:06:07+00:00\",\"description\":\"Learn about SYNE1 Ataxia, a rare neurodegenerative disorder. 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