{"id":26238,"date":"2025-05-07T16:45:23","date_gmt":"2025-05-07T21:45:23","guid":{"rendered":"https:\/\/www.ataxia.org\/?page_id=26238"},"modified":"2025-05-12T11:49:06","modified_gmt":"2025-05-12T16:49:06","slug":"xlca","status":"publish","type":"page","link":"https:\/\/www.ataxia.org\/xlca\/","title":{"rendered":"XLCA"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"26238\" class=\"elementor elementor-26238\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3faf2f55 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"3faf2f55\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-67e6c725\" data-id=\"67e6c725\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-72f31a34\" data-id=\"72f31a34\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3c6cd0f5 elementor-widget elementor-widget-heading\" data-id=\"3c6cd0f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-xl\">X-Linked Cerebellar Ataxias <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6526ba60 elementor-widget elementor-widget-spacer\" data-id=\"6526ba60\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ef401c elementor-widget elementor-widget-text-editor\" data-id=\"3ef401c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #000000;\">A collection of resources for individuals and families affected by X-Linked Cerebellar Ataxias (XLCA).<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-13753e40 elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"13753e40\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-20 elementor-top-column elementor-element elementor-element-72ef3590\" data-id=\"72ef3590\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-70ad09d8 elementor-widget elementor-widget-text-editor\" data-id=\"70ad09d8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#webinars\"><strong>WEBINARS<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-20 elementor-top-column elementor-element elementor-element-321d8fa2\" data-id=\"321d8fa2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-685b3510 elementor-widget elementor-widget-text-editor\" data-id=\"685b3510\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#pipeline\"><strong>RESEARCH<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-20 elementor-top-column elementor-element elementor-element-5c1fc140\" data-id=\"5c1fc140\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-34a4606d elementor-widget elementor-widget-text-editor\" data-id=\"34a4606d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#factsheet\"><strong>INFORMATION<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-20 elementor-top-column elementor-element elementor-element-401d4652\" data-id=\"401d4652\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-21787414 elementor-widget elementor-widget-text-editor\" data-id=\"21787414\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#scasource\"><strong>RESEARCH NEWS<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-20 elementor-top-column elementor-element elementor-element-7fd3d00a\" data-id=\"7fd3d00a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-37647b4a elementor-widget elementor-widget-text-editor\" data-id=\"37647b4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/interland3.donorperfect.net\/weblink\/weblink.aspx?name=E79738&amp;id=285\" target=\"_blank\" rel=\"noopener\"><strong>BECOME A MEMBER &gt;&gt;<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6e1da81f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6e1da81f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7849916e\" data-id=\"7849916e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-391a8f6e elementor-widget elementor-widget-spacer\" data-id=\"391a8f6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22049324 elementor-widget elementor-widget-text-editor\" data-id=\"22049324\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>X-Linked Cerebellar Ataxias (XLCA) are a group of ataxia disorders caused by genetic mutations on the X chromosome. XLCA leads to problems with balance and coordination, as well as other symptoms depending on the type of XLCA. For complete information about symptoms, diagnosis, and treatment of Ataxia, visit our\u00a0<span style=\"text-decoration: underline;\"><strong><a href=\"https:\/\/www.ataxia.org\/what-is-ataxia\/\">What is Ataxia?<\/a><\/strong><\/span>\u00a0page.\u00a0\u00a0This page contains NAF&#8217;s resources that are specific to XLCA.\u00a0\u00a0<\/p><p>This webpage is focused on rarer forms of XLCA. If you are looking for information on Fragile X-associated tremor\/ataxia syndrome (FXTAS), please visit our <span style=\"text-decoration: underline;\"><strong><a href=\"https:\/\/www.ataxia.org\/FXTAS\/\">FXTAS information page<\/a><\/strong><\/span>.<\/p><p><strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/interland3.donorperfect.net\/weblink\/weblink.aspx?name=E79738&amp;id=285\" target=\"_blank\" rel=\"noopener\">Sign up for our mailing list<\/a><\/span><\/strong> to stay up-to-date on Ataxia news.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5101751 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5101751\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-44130bb7\" data-id=\"44130bb7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5490f476 elementor-widget elementor-widget-spacer\" data-id=\"5490f476\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-13d27229 elementor-widget elementor-widget-menu-anchor\" data-id=\"13d27229\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"webinars\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d4e71ea elementor-widget elementor-widget-heading\" data-id=\"2d4e71ea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Webinar<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-52be4615 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"52be4615\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d705e88 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d705e88\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9956baa\" data-id=\"9956baa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bf914b0 elementor-widget elementor-widget-heading\" data-id=\"bf914b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">All About X-Linked Cerebellar Ataxias\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-40aac269 elementor-widget elementor-widget-video\" data-id=\"40aac269\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=0ijlPbThS2k&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-470e40bf elementor-widget elementor-widget-text-editor\" data-id=\"470e40bf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em><strong>Presented by Ginevra Zanni, MD, PhD and Enrico Bertini, MD<\/strong><\/em><\/p><p>Experts joined us to take a look at the causes and symptoms of X-Linked Cerebellar Ataxia (XLCA), the typical diagnostic journey for those affected, what to expect for clinical care, and an overview of current research into these diseases. XLCA includes several different conditions, such as X-linked spinocerebellar ataxia, X-linked ataxia with spasticity, X-linked ataxia with deafness, X-linked ataxia with dementia, X-linked congenital ataxia, Oligophrenin-1 syndrome, CASK syndrome, Christianson syndrome, and X-linked adrenoleukodystrophy-ataxic variant.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5ebfd487 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5ebfd487\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3415aa7f\" data-id=\"3415aa7f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3841cb61 elementor-widget elementor-widget-spacer\" data-id=\"3841cb61\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d1547ff elementor-widget elementor-widget-text-editor\" data-id=\"5d1547ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>NAF offers webinars on many topics to help you live better with Ataxia. Visit\u00a0<span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.ataxia.org\/webinars\" target=\"_blank\" rel=\"noopener\">www.ataxia.org\/webinars<\/a><\/span>\u00a0to find other helpful presentations.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-46782cb1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"46782cb1\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1125f6df\" data-id=\"1125f6df\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-64f4474c elementor-widget elementor-widget-spacer\" data-id=\"64f4474c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f669244 elementor-widget elementor-widget-menu-anchor\" data-id=\"4f669244\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"pipeline\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31ae2311 elementor-widget elementor-widget-heading\" data-id=\"31ae2311\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Participate in Research and Treatment Development <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-194b3a01 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"194b3a01\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-12462676 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"12462676\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1d6db3fb\" data-id=\"1d6db3fb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1d937228 elementor-widget elementor-widget-text-editor\" data-id=\"1d937228\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Participating in a research study or clinical trial is one way to take an active role in furthering understanding and treatment of Ataxia. It is also a way to get access to new treatment options before they are widely available. To find studies that are enrolling patients, visit our\u00a0<span style=\"text-decoration: underline;\"><strong><a href=\"https:\/\/www.ataxia.org\/help-develop-new-treatments\/\" target=\"_blank\" rel=\"noopener\">Help Develop New Treatments<\/a><\/strong><\/span>\u00a0page.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-539c69bc elementor-align-center elementor-widget elementor-widget-button\" data-id=\"539c69bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.ataxia.org\/help-develop-new-treatments\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Find a Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6c1f3137 elementor-widget elementor-widget-spacer\" data-id=\"6c1f3137\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fafe9ad elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fafe9ad\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3b049a06\" data-id=\"3b049a06\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-57b2e7af elementor-widget elementor-widget-spacer\" data-id=\"57b2e7af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-101e18c0 elementor-widget elementor-widget-menu-anchor\" data-id=\"101e18c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"factsheet\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-272d2e0f elementor-widget elementor-widget-heading\" data-id=\"272d2e0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">XLCA Information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d4dfcdd elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1d4dfcdd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6744fddd elementor-widget elementor-widget-text-editor\" data-id=\"6744fddd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>X-Linked Cerebellar Ataxias (XLCA) are a group of rare neurodegenerative disorders. There are many types of XLCA, with new forms of XLCA still being discovered. Each type of XLCA is caused by mutations in different genes. Some genes that cause XLCA have been identified, and others have not. <br \/>The frequency of XLCA disorders varies. Most are quite rare. However, some forms of XLCA are more common, such as FXTAS (1 in 8,000 people) and Rett syndrome (1 in 10,000 women).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55c5ba22 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"55c5ba22\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2025\/05\/X-Linked-Cerebellar-Ataxias-Fact-Sheet.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Printable Fact Sheet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3935e36f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3935e36f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-21873a79\" data-id=\"21873a79\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-53413006 elementor-widget elementor-widget-heading\" data-id=\"53413006\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">XLCA Symptoms<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ca8f0a8 elementor-widget elementor-widget-text-editor\" data-id=\"7ca8f0a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Like many other forms of Ataxia, XLCA is marked by poor balance and coordination. In fact, the word Ataxia means incoordination. There can also be problems coordinating muscles that control speech and swallowing.<\/p><p>The other symptoms that someone with XLCA experiences depend on their specific ataxia type.<\/p><ul><li><strong>X-linked spinocerebellar ataxia (SCA-X1) <\/strong>is caused by mutations in the <em>ATP2B3<\/em> Symptoms are usually present from birth. This includes ataxia, decreased muscle tone, delayed early developmental milestones, difficulty speaking, and slow eye movements. Symptoms are known to vary between patients, even within the same family.<\/li><li><strong>X-linked ataxia with spasticity (SCA-X2)<\/strong> is caused by mutations in an unknown gene. Symptoms are present from birth. This includes ataxia, spasticity, head tremor, intellectual disability, and premature death.<\/li><li><strong>X-linked ataxia with deafness (SCA-X3)<\/strong> is caused by mutations in an unknown gene. Symptoms develop during infancy. This includes ataxia, deafness, decreased muscle tone, delayed early developmental milestones, cross-eyed gaze, and premature death.<\/li><li><strong>X-linked ataxia with dementia (SCA-X4)<\/strong> is caused by mutations in an unknown gene. Symptoms first appear in childhood, and progress over time. Initial symptoms include delayed walking and tremor. In their teenage years, people with SCA-X4 develop mild but progressive ataxia. In their mid-thirties, patients develop progressive dementia, leading to premature death in their sixties.<\/li><li><strong>X-linked congenital ataxia (SCA-X5)<\/strong> is caused by mutations in an unknown gene. Ataxia symptoms are present from birth, along with eye and speech symptoms. Symptoms tend to improve with age.<\/li><li><strong>X-linked sideroblastic anemia with spinocerebellar ataxia (SCA-X6)<\/strong> is caused by mutations in the <em>ABCB7<\/em> Symptoms begin during infancy. They include slowly progressive ataxia and anemia. Some patients also develop speech symptoms, eye symptoms, or spasticity.<\/li><li><strong>Oligophrenin-1 syndrome<\/strong> is caused by mutations in the <em>OPHN1<\/em> Symptoms first appear in childhood. They include ataxia, decreased muscle tone, intellectual disability, and delayed early developmental milestones. Some patients also experience seizures. Symptoms are known to vary between patients, even within the same family.<\/li><li><strong>CASK syndrome <\/strong>is caused by mutations in the <em>CASK<\/em> Symptoms first appear in childhood. People with CASK syndrome tend to have smaller heads, intellectual impairment, and ataxia. Some people may develop hearing loss or eye symptoms. Some people with CASK syndrome have seizures, but this is more common for girls than boys.<\/li><li><strong>Christianson syndrome<\/strong> is caused by mutations in the <em>SLC9A6\u00a0<\/em> Symptoms first appear in early childhood. They include ataxia, intellectual disability, impaired eye movements, decreased muscle tone, having small head, seizures, delayed developmental milestones, and developmental regression.<\/li><li><strong>Fragile X-associated tremor\/ataxia syndrome (FXTAS)<\/strong> is caused by mutations in the <em>FMR1<\/em> Symptoms begin in late adulthood. Please visit our <a href=\"https:\/\/www.ataxia.org\/FXTAS\/\"><span style=\"text-decoration: underline;\"><strong>FXTAS information page<\/strong><\/span><\/a> for more information.<\/li><li><strong>X-linked cerebellar hypoplasia and spondyloepyphiseal dysplasia<\/strong> is caused by mutations in the\u00a0<em>RPL10<\/em> Symptoms first appear in childhood. They include ataxia, intellectual disability, having a small head, slowed growth, seizures, and minor facial anomalies.<\/li><li><strong>Allan\u2013Herndon\u2013Dudley syndrome (AHDS)<\/strong> is caused by mutations in the <em>MCT8<\/em> Symptoms first appear in early childhood. They include ataxia, intellectual disability, difficulty speaking, spasticity, weakness, reduced muscle mass, and delay of developmental milestones.\u00a0<\/li><li><strong>Rett syndrome (RTT)<\/strong> is caused by mutations in the <em>MECP2<\/em> Symptoms begin in early childhood. After typical development, patients with Rett syndrome regress around age 6-18 months. They develop ataxia, repetitive hand movements, breathing challenges, seizures, epilepsy, loss of speech, and increased reflexes. Rett syndrome is more common in girls than boys. Please visit the <span style=\"text-decoration: underline;\"><strong><a href=\"https:\/\/www.rettsyndrome.org\/about-rett-syndrome\/understanding-rett-syndrome\/\" target=\"_blank\" rel=\"noopener\">International Rett Syndrome Foundation<\/a><\/strong><\/span> to learn more.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-552a2614 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"552a2614\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5773f1c2\" data-id=\"5773f1c2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3f7fd825 elementor-widget elementor-widget-heading\" data-id=\"3f7fd825\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">XLCA Prognosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-489322d4 elementor-widget elementor-widget-text-editor\" data-id=\"489322d4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The prognosis for people with XLCA depends on their specific ataxia type. Many forms begin during childhood and progress over time. Treatments such as physiotherapy, occupational therapy, and speech-language therapy can also significantly improve the lives of people with XLCA. Depending on a person\u2019s type of XLCA, there may also be symptomatic or disease-specific treatments available.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-31af6750 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"31af6750\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1d7b5085\" data-id=\"1d7b5085\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-40fa7e32 elementor-widget elementor-widget-heading\" data-id=\"40fa7e32\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">XLCA Genetics<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c78a7b elementor-widget elementor-widget-text-editor\" data-id=\"5c78a7b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>XLCA is a group of genetic disorders, which means that they are inherited diseases. Each type of XLCA is caused by mutations in different genes.<\/p><p>Genes are microscopic structures within the cells of our bodies that contain instructions for every feature a person inherits from his or her parents. The abnormal gene responsible for different forms of XLCA is passed along from generation to generation by unaffected family members who carry it. Sometimes, these mutations will also randomly develop in someone when they are conceived.<\/p><p>XLCA are X-linked disorders, meaning that the genes that cause these disorders are found on the X chromosome. Usually, women have two X chromosomes (XX) and men have one X and one Y chromosome. Due to this difference, X-linked disorders impact men and women differently.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d9bd34e elementor-widget elementor-widget-heading\" data-id=\"d9bd34e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">X-Linked Recessive Ataxia<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e059c89 elementor-widget elementor-widget-text-editor\" data-id=\"e059c89\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Most forms of X-linked ataxia are recessive.<\/p><p>Men who carry the mutation for an X-linked recessive ataxia will develop that condition. This is because they only have one X chromosome, which is affected by the ataxia mutation. Men are more commonly impacted by X-linked recessive ataxia.<\/p><p>Women who have one copy of the mutation for an X-linked recessive ataxia will <u>not<\/u> usually develop the condition. This is because they have two X chromosomes, and the unaffected X chromosome can protect them from developing symptoms. People who have a mutation for an X-linked recessive ataxia without developing symptoms are called carriers. Depending on the type of XLCA, some carriers may also experience mild features of the disorder. If a woman has two copies of the mutation for an X-linked recessive ataxia, one on each X chromosome, then she will develop that condition.<\/p><p>The likelihood of passing on an X-linked recessive ataxia is complicated. It depends on the sex of the parent passing on the gene, and the sex of the child receiving the gene. You can learn more about X-linked recessive condition inheritance patterns through <strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.genomicseducation.hee.nhs.uk\/genotes\/knowledge-hub\/x-linked-recessive-inheritance\/#male-vs-female-inheritance-patterns\" target=\"_blank\" rel=\"noopener\">the NHS National Genomics Education Programme<\/a><\/span><\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-20d591b elementor-widget elementor-widget-heading\" data-id=\"20d591b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">X-Linked Dominant Ataxia<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b0011e5 elementor-widget elementor-widget-text-editor\" data-id=\"b0011e5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Only one copy of a mutation for an X-linked dominant ataxia is needed to develop the condition. Thus, both men and women can be affected by X-linked dominant ataxia, if they have one copy of the mutated gene. Since they only have one X chromosome, men tend to have more severe symptoms than women. Sometimes the symptoms are so severe, boys with X-linked dominant ataxia either die in utero or shortly after birth. Rett syndrome is one example of an X-linked dominant ataxia.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f53f98 elementor-widget elementor-widget-heading\" data-id=\"5f53f98\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Genetic Counseling and Testing<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d2cd00 elementor-widget elementor-widget-text-editor\" data-id=\"2d2cd00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Gene tests can be performed for diagnostic purposes to determine what kind of Ataxia is within a person or family. Genetic testing can also be done, in some circumstances, even before there are symptoms to determine whether a person carries the abnormal gene or genes that cause Ataxia. This is called predictive or presymptomatic testing. A gene test can also be used to determine whether a fetus has an abnormal Ataxia gene. This is called prenatal testing. Anyone who is considering a predictive or prenatal test should consult with a genetic counselor to discuss the reasons for the test, the possible outcomes, and how those outcomes might affect the person emotionally, medically, or socially.\u202f<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d10bca5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d10bca5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4fec3af\" data-id=\"4fec3af\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-34f510ef elementor-widget elementor-widget-heading\" data-id=\"34f510ef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">XLCA Diagnosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-417238e4 elementor-widget elementor-widget-text-editor\" data-id=\"417238e4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A neurologic examination can determine whether a person has symptoms typical of XLCA. A neurologist is often the most helpful specialist in recognizing symptoms and diagnosing the disease that causes Ataxia.<\/p><p>Providing a detailed family history is critical for accurately diagnosing X-linked conditions. There are several potential follow-up tests. MRI brain imaging may be used to confirm cerebellar atrophy. Metabolic testing may be used to rule out other forms of ataxia that have similar symptoms to XLCA. A definitive diagnosis of XLCA is established following genetic testing. This confirms that someone has a mutation that causes XLCA.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1b8f6ede elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1b8f6ede\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-13c346b1\" data-id=\"13c346b1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-317766af elementor-widget elementor-widget-spacer\" data-id=\"317766af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-62ba2059 elementor-widget elementor-widget-menu-anchor\" data-id=\"62ba2059\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"scasource\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7146f3d elementor-widget elementor-widget-heading\" data-id=\"7146f3d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">XLCA Research News<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b6e1623 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"3b6e1623\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54e18ef0 elementor-widget elementor-widget-text-editor\" data-id=\"54e18ef0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>SCAsource provides Ataxia research news, directly from researchers to the Ataxia community. <span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Visit\u00a0<\/span><strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.ataxia.org\/SCAsource\" target=\"_blank\" rel=\"noopener\">SCAsource<\/a><\/span><\/strong><span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"> to see their full collection.\u00a0<\/span>Here is a collection of articles related to XLCA.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-341d5f19 elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-posts--thumbnail-top elementor-widget elementor-widget-posts\" data-id=\"341d5f19\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;3&quot;,&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:35,&quot;sizes&quot;:[]},&quot;classic_row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19415 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-arsacs tag-ataxia tag-english tag-genetic-testing\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-300x157.png\" class=\"attachment-medium size-medium wp-image-20153\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/09\/Featured-Image-Size-3.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is recessive ataxia?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tNovember 29, 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>What is a recessive disorder? A recessive disorder is one that has a specific disease mechanism. For a recessive disorder to occur, both copies of the causative gene must be <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-recessive-ataxia\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19451 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-dna tag-english tag-genetic-testing\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"288\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1-300x288.webp\" class=\"attachment-medium size-medium wp-image-19548\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1-300x288.webp 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1.webp 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is a Gene?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tDecember 4, 2020\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>A gene is the basic physical unitof heredity. Every living cell contains genetic information that determines an organism\u2019s development, form, and function. This genetic information is encoded by two macromolecules: <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-22296 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-spasticity tag-symptoms\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-spasticity\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Apr-19-Featured-Image-Sized-300x157.png\" class=\"attachment-medium size-medium wp-image-22278\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Apr-19-Featured-Image-Sized-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Apr-19-Featured-Image-Sized-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Apr-19-Featured-Image-Sized-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Apr-19-Featured-Image-Sized.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-spasticity\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Spasticity?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tApril 19, 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Spasticity is a condition where muscles involuntarily stiffen, impeding normal smooth movements. Spasticity can present in varying severities with varying impacts on daily life. For example, minor spasticity resulting in <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-spasticity\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-23243 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-augmentative-and-alternative-communication tag-english tag-speech-language-pathology\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-augmentative-and-alternative-communication-aac\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/May-10-Featured-Image-300x157.png\" class=\"attachment-medium size-medium wp-image-23244\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/May-10-Featured-Image-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/May-10-Featured-Image-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/May-10-Featured-Image-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/02\/May-10-Featured-Image.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-augmentative-and-alternative-communication-aac\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Augmentative and Alternative Communication (AAC)?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tMay 10, 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Augmentative and Alternative Communication (AAC) is an umbrella term that has many meanings. Simply put, AAC is every way we communicate other than speaking. At its core, AAC uses symbols. <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-augmentative-and-alternative-communication-aac\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-25248 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-symptoms\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-are-pyramidal-signs\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/jan-24-Featured-Image-1-300x157.png\" class=\"attachment-medium size-medium wp-image-25249\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/jan-24-Featured-Image-1-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/jan-24-Featured-Image-1-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/jan-24-Featured-Image-1-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/jan-24-Featured-Image-1.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-are-pyramidal-signs\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What are Pyramidal Signs?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tJanuary 24, 2025\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Have you ever wondered what part of your nervous system is helping move the muscles of your body? Or your head? An important part of our central nervous system called <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-are-pyramidal-signs\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-25266 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-genetics\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-de-novo-mutation\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/May-2-Featured-Image-300x157.png\" class=\"attachment-medium size-medium wp-image-25267\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/May-2-Featured-Image-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/May-2-Featured-Image-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/May-2-Featured-Image-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/12\/May-2-Featured-Image.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-de-novo-mutation\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is a De Novo Mutation?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\tMay 2, 2025\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>For healthy function, our body performs many essential cellular processes mediated by the molecules created within us. This construction is based on a molecule called DNA, which acts as an <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-de-novo-mutation\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4cfce04c elementor-widget elementor-widget-spacer\" data-id=\"4cfce04c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>X-Linked Cerebellar Ataxias A collection of resources for individuals and families affected by X-Linked Cerebellar Ataxias (XLCA). WEBINARS RESEARCH INFORMATION RESEARCH NEWS BECOME A MEMBER &gt;&gt; X-Linked Cerebellar Ataxias (XLCA) <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-de-novo-mutation\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":4,"featured_media":21512,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-26238","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>XLCA - National Ataxia Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ataxia.org\/xlca\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XLCA - National Ataxia Foundation\" \/>\n<meta property=\"og:description\" content=\"X-Linked Cerebellar Ataxias A collection of resources for individuals and families affected by X-Linked Cerebellar Ataxias (XLCA). WEBINARS RESEARCH INFORMATION RESEARCH NEWS BECOME A MEMBER &gt;&gt; X-Linked Cerebellar Ataxias (XLCA) Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ataxia.org\/xlca\/\" \/>\n<meta property=\"og:site_name\" content=\"National Ataxia Foundation\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-12T16:49:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/05\/Ataxia-Type-Featured-Image.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"13 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/\",\"name\":\"XLCA - National Ataxia Foundation\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Ataxia-Type-Featured-Image.png\",\"datePublished\":\"2025-05-07T21:45:23+00:00\",\"dateModified\":\"2025-05-12T16:49:06+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Ataxia-Type-Featured-Image.png\",\"contentUrl\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/Ataxia-Type-Featured-Image.png\",\"width\":1200,\"height\":628},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/xlca\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.ataxia.org\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"XLCA\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#website\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/\",\"name\":\"National Ataxia Foundation\",\"description\":\"Connecting Ataxia families, researchers, clinicians and the community\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ataxia.org\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#organization\",\"name\":\"National Ataxia Foundation\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2017\\\/08\\\/logo_Ataxia.jpg\",\"contentUrl\":\"https:\\\/\\\/www.ataxia.org\\\/wp-content\\\/uploads\\\/2017\\\/08\\\/logo_Ataxia.jpg\",\"width\":286,\"height\":100,\"caption\":\"National Ataxia Foundation\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ataxia.org\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"XLCA - National Ataxia Foundation","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ataxia.org\/xlca\/","og_locale":"en_US","og_type":"article","og_title":"XLCA - National Ataxia Foundation","og_description":"X-Linked Cerebellar Ataxias A collection of resources for individuals and families affected by X-Linked Cerebellar Ataxias (XLCA). 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